TCR V Beta8.1 antibody

Catalog No. ABIN2665401

This Mouse Monoclonal antibody specifically detects in WB and IF. It exhibits reactivity toward Mouse.

Quick Overview for TCR V Beta8.1 antibody (ABIN2665401)

Target: TCR V Beta8.1

Reactivity: Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Clone: MR5-2

Product Details

Purification: The antibody was purified by affinity chromatography.

Isotype: IgG2a kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C.

Target Details

Target: TCR V Beta8.1

Background: Vβ8 T cell receptor (TCR Vβ8) subfamily has three members, Vβ8.1, 8.2, and 8.3. These subfamily members are variants of the TCR β chain that along with the TCR α chain forms the TCR heterodimer, responsible for the recognition of peptides presented by the MHC molecules. Murine Vβ8+ T cells recognize the superantigen staphylococcal enterotoxin B (SEB), in vivo administration of SEB results in the negative selection of Vβ8+ cells in the thymus. Vβ8 is one of the most frequently found β chains on the infiltrating T cells in the brain of mice with experimental autoimmune encephalomyelitis (EAE), and on the T cells response to Toxoplasma gondii.